CHARM Therapeutics

๐Ÿ“‚ Healthtech๐Ÿ“‚ Artificial Intelligence๐Ÿ“ Londra๐Ÿ—“๏ธ Founded: 2021

CHARM Therapeutics uses DragonFold, a 3D deep learning-based protein-ligand prediction AI platform, to identify and validate therapeutic molecules with high specificity against complex protein targets.

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Podcast Episode

๐ŸŽ™๏ธ Deep Dive

Daily News - 2 September 2025

Listen to the episode

About CHARM Therapeutics

CHARM Therapeutics is a London-based biopharmaceutical startup founded in 2021 by Laksh Aithani (ex-Exscientia) and supported by David Baker (Breakthrough Prize winner for protein design). The company developed DragonFold, a 3D deep learning-based AI protein-ligand prediction platform that identifies molecules capable of specifically binding to difficult oncology protein targets. The platform was developed as an evolution of protein structure prediction models (such as AlphaFold). In 2025 it raised โ‚ฌ68.5M in a Series B to advance its oncology inhibitor pipeline.

Market & Clients

Key Customers

Pharmaceutical and biotech companies seeking new therapeutic molecules for high-need oncology targets.

Geographic Presence

GB

Funding & Investors

Funding Rounds

  • 2025 - Series B: โ‚ฌ68M

Key Investors

F-Prime CapitalOrbiMedGeneral CatalystKhosla Ventures

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Sources

๐ŸŽ™๏ธ Scalable Podcast โ€” European startup stories ยท ๐Ÿ‡ฎ๐Ÿ‡น in Italian
Spotify ๐ŸŽง Apple