Startups in Roma: ecosystem, companies and strengths

Italy's emerging Central-South hub, with a strong vocation for govtech, digital tourism and energy transition, supported by excellent technical universities.

~294 startup VC-backed/tracciate da Dealroom; ~443 secondo StartupBlink
Estimated startups

Why Roma matters in the European startup ecosystem

Rome is Italy's second startup pole, still far from Milan but growing thanks to public programmes, major state entities (ENI, ENEL, Leonardo, Lazio Innova) and a quality university ecosystem. La Sapienza, LUISS and Roma Tre generate strong technical and managerial talent. The city has a natural vocation for govtech, digital tourism, media and energy transition. Deep VC ecosystems are still lacking, but initiatives like LVenture Group and CDP Venture Capital are closing the gap. The presence of large state corporates offers B2G opportunities that are hard to find elsewhere.

Why it works

  • Distinctive assets in space and govtech
  • Relevant university scale
  • Still-untapped spinout potential

Historical growth

Rome grows more slowly than northern Italian poles, but has carved out a space in the space economy, govtech and digital services. Its potential is higher than the traction it has expressed so far.

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Strengths of Roma

  • Italy's institutional capital
  • Large university base
  • Strength in space and public innovation
  • Seed has improved thanks to public instruments and accelerators. For Series A and growth, Rome's market remains much weaker than Milan.
  • Telecom, utilities, defence, space and public administration create demand in regulated sectors. Rome is strongest where complex procurement matters.

Weaknesses and limitations

  • Limited local private capital
  • Few exit role models
  • Lower density of repeatable startups than Milan

Key startups in Roma

&100

&100 provides consulting and services dedicated to newsstands. Its main offerings include specific consulting services, access to the Edicole&100 community, and commercial agreements.

123BUFFET A RESPONSABILITA LIMITATA

123buffet is the quick and easy way to organize your refreshments by choosing from the quality solutions offered by our partners.

20ENERGY

20energy is an Innovative Startup born in 2020 to develop, produce and market LYBRA on the national and international market. LYBRA is a speed absorber that accesses a new one

2M . START-UP INNOVATIVA

Videocasa: real estate portal that allows rental and sale to be concluded in a few days. Discover the new innovative method. Guaranteed result!

7 ART STUDIOS

Film productions for the big screen. Film productions for the big screen

7HC

Discover new possibilities INTERNET OF THINGS & CLOUD COMPUTING Our software solutions manage the storage, processing and transmission of data through the Cloud technique

ACTIVE-ITALIA

Green Chemistry for the isolation and purification of Oleacein, Oleocanthal and Total Phenolic Fraction (TPF) from EVOO (Extra Virgin Olive Oil).

AFL SOLUTIONS

Let the AI do the sending so you can manage the conference. Earendel automates abstract reviews, instantly matches reviewers, and keeps your academic conference on track

AGON

VISION & VALUE + PERFORMANCE Follow a manual added link VISION & VALUE Follow a manual added link + PERFORMANCE The ideal tool to increase competitive performance

AGRIRED SOCIETA AGRICOLA INNOVATIVA A RESPONSABILITA LIMITATA

AgriRed - Innovative Agricultural Society. Aquaponic agritech hub in Tarquinia. Verlizie products: aromatic herbs and zero residue salads. #WeGrowSustainability

AICLO

Aiclo is the Conversation Intelligence platform that acquires all conversations and transforms them into insights for management and the commercial team, to make better decisions

AIDEA LABS

The "mission" of Aidea Labs consists in developing software that allows optimizing the "commercial funnels" of companies operating on the "web".

AILEVEN DIGITAL MEDIA

THE MOST ENGAGING FOOTBALL EXPERIENCE A GAME ECOSYSTEM 01 PLAY your table football match using your personal strategy and managing your tokens to always be ready and

AIO

We have rethought the iterative and manual processes of human work, thanks to the support of Artificial Workers.

AIWAY

Safety and innovation meet in the automated analysis of the road surface and road markings to guarantee safer roads and more efficient interventions.

AKME CAPITAL

Explore Akme Capital's AI fintech platform: MIDA for advanced risk management and FutureSight, an AI-powered cybersecurity solution designed to

ALGAEBIOMED

Inspired by nature, we follow science. It targets producers and integrators in the automotive, robotics, and medical sectors.

ALL EVENTS FACTORY

A new Event Organization company that stands out for its extraordinary combination of skills and professionalism.

ANTALIA AI

7 AI collaborators for your office. They manage orders, write documents, send emails, answer the phone.

APISHARE

We listen to our interlocutors, we grow with them and we share their needs and requirements, helping them to transform challenges into opportunities.

APPGRADE

Inspire your way to stay fit! Discover the benefits for wellness professionals.

APS

Play Seven designs and installs safe and fun Playgrounds and Playgrounds for children of all ages, even with a fitness area.

AR-IOS

The application of PEFs, through bacterial inactivation, guarantees the food safety of the products and the protection of the organoleptic characteristics of the treated products (e.g.

ARCHEOVERSE

ArcheoVerse is an innovative start-up dedicated to the study, development and communication of digital technologies applied to cultural heritage and market analyzes for the use of heritage

ARPI TECHNOLOGY

Places DISCOVER THE PAST Places of Ancient Rome available to be rewound 9 historical reconstructions already available in VR and 8 more coming to your phone soon!

ARTUP

The ARTup revolution is finally here Decentralized digital art ecosystem 1,000 users 30,000 NFTs Market capitalization 00,000 transactions 00,000 transactions What is ARTup?

ASIMOV AI

monitoring processes Simplify your monitoring processes through our advanced and intuitive software.

AUREA IA

Welcome to Aurea IA An innovation center dedicated to territorial security and the protection of cultural heritage.

AUTOMYO S.R.L.

Intelligent integration and automation designed for enterprise workflows and operational efficiency.

Ailyn

Who I am They told me that I am a predictive artificial intelligence.

Alethes

How can artificial intelligence be used in contract management? Among the main offerings are the use of artificial intelligence and machine learning to build predictive analysis algorithms - Open

B.I.A

Technological solutions of the future Simple and innovative digitalization Digital solutions to elevate your business BIA is committed to making technology simple and accessible, promoting

BABETECH

Babetech EnergyBeat. Discover the smart platform for monitoring the production and consumption of production machines

BAZR

The first Italian live shopping platform. Download the app and enjoy the show! Get into the heart of shopping Download the app Everything you want in one app Bazr is the app to buy the products you

BAZUEL

Apr 22, 2025 · You can use the UserCheck API to instantly detect and block forwarding email domains like bazuel.com. It's a quick setup that can get better

BEEINCLUSION

BeeInclusion is the first 360° social search engine. It was created with the aim of making accessible services geolocalised in the area and indexed based on a single platform available

BEERFINDER

Trovabirre, the revolution in the distribution of craft beers in Italy: discover the offers and advantages for breweries, pubs, restaurants and pizzerias.

BETADYNAMIQ

Betadynamiq: Unlock the full potential of your devices and take your business to new heights with our cutting-edge Edge AI technology.

BETTERCARS

We are a strategic partner for the core business of car dealers and for the peace of mind of their customers in purchasing the best cars.

BHAVE

Bhave is the innovative start-up that uses AI for behavior analysis in the health world

BIOLT SEMPLIFICATA

Therapies with bioactive liposomes The emergence of MDR pathogens is causing the increase in serious infections, which are pharmacologically difficult to treat.

BITLOGIS . IN LIQUIDAZIONE

Artificial intelligence - We founded BitLogis to follow a great passion of ours, teaching machines to do what humans now do with difficulty.

BLUTECH

PROJECTS An ambitious project through which we would like to surpass ourselves and bring a positive impact to the world of optics with a new product.

BMP

Wear a Unica Shirt, produced with the best yarns, made with care and by hand in Italy by our expert tailors. A haute couture jewel for a wardrobe that goes beyond seasons and seasons

BOATEAT

Experience the finest artisan foods and exceptional wines, delivered with impeccable care to private villas and yachts throughout the Costa Smeralda.

BOBIS . IN LIQUIDAZIONE

Queens Casino for Fans: Start your journey with a generous welcome package and win amazing prizes. Play the most popular games and withdraw your funds whenever you want.

BOOSTED AI

Enhance Your Training with Artificial Intelligence

BOOSTERGY

We are an agency and we help you with tailor-made marketing solutions that are successful in meeting the challenges of the energy market.

BRIEF

Brief combines AI and voice to make every text a unique audio experience. Create thematic channels, share content and inspire your community in minutes.

BUTAC

BUTAC fights against hoaxes, misinformation, gratuitous alarmism and online fraud. Passion for correct information, passion for the truth on butac.it.

Big Data Innovation Group

Improve your business idea with tailored digital solutions. Among the main offerings, we provide the individual pieces of the puzzle.

CAELUS S.R.L.

Software platform that digitizes the construction industry for improved project management and operations.

CALEJO SMART WATER

Transforming industrial operations with AI-based insights and automation. Its main offerings include solutions for the digitalization of industrial water and wastewater management.

CAROL

A new idea of general medicine.

CAUSEWAY THERAPEUTICS ITALIA

The Tendon Health Company: Causeway Therapeutics is developing first-in-class microRNA therapeutics with the potential to improve the quality of life of those suffering from tendinopathy.

CEREBRUM VR

Cerebrum VR is a Virtual Reality App for Cognitive Rehabilitation designed for Mental Health workers.

CHARING CROSS TECHNOLOGIES

Offering expert technology and consulting services in Canada, specializing in healthcare, supply chain, SAP, mergers and acquisitions, digital transformation and more.

CHIMERA TECH

Innovative startup that combines artificial intelligence, engineering and design to transform complexity into concrete and sustainable value.

CLINICAL EYE

Already for 4 visits a month, the competitiveness of our solution is easily demonstrable.

COGITAI

Useful artificial intelligence

COMINGUP

We are able to conceive, organize and promote events, conferences and working groups, following all the strategic and organizational phases (creative concept, selection and proposal of the location

COMMUNITY TURBO

"We are all different - everyone deserves what they merit. " Among the main offerings is the development of more meritocratic communities.

COMUNICO

Comunico Online is an innovative digital project that allows you to enrich the educational offering with modular educational paths, perfect for self-learning, asynchronous study and

CONSULENS S.R.L.

Tax management software designed to streamline and automate fiscal processes for businesses, improving compliance and reporting efficiency.

CONSULTALA

The Software for Labor Consultants. Talk to our sales representative now on WhatsApp for immediate consultation!

COOL TECH

Cool Tech is dedicated to the development, production and marketing of products and services with high technological value.

CREWREEL SERVICES

CrewReel: Innovate film and television production with advanced software solutions to simplify and digitize workflows, improving collaboration and efficiency

CYBERSA S.R.L.

Cybersecurity company delivering innovative, tailored protection solutions for businesses facing evolving digital threats.

CYLOCK

Better than a Vulnerability Assessment, Safer than a Penetration Test. Test with one click: servers, VMs, websites and internal networks. Furthermore, thanks to OSINT you can discover your company

DATA0 1

DATA01 srl — Innovative R&D startup: AIoT integrated systems for environmental monitoring, data analysis and predictive solutions for Cultural and Environmental Heritage.

DATAMIND

Not only Artificial Intelligence and Data Management, but also free training for young people. Next Generation Work - Developer and Data-science.

DEBEST

Discover the world of digital collectibles

DEEPAGENT

Leading Italian company of AI Voice Agents. They qualify leads, schedule appointments and manage customer service 24/7. Costs reduced by 80%

DEEPPLANTS

Protect tomorrow, innovate today: promoting resilience for a climate positive future

DOTX AUTOMATION S.R.L.

DOTX powers the future with industrial automation and sustainable energy solutions.

Data Quality Lab

Data Quality Lab is a start-up specialized in measuring the characteristics of data, software and services.

Exein

Rome-based embedded cybersecurity startup protecting IoT devices with on-device AI at the firmware level. €170M raised, MediaTek Genio partnership and an installed base of 1.5 billion devices.

Fitprime

Fitprime, founded in 2016 in Rome, is an Italian corporate wellness platform. It serves over 200 client companies and offers fitness, nutrition and mental health support programs to more than 400,000 employees. In 2024 it was acquired by Wellhub.

GEOSONAR S.R.L.

AI brand visibility intelligence platform that analyses and optimises how brands are cited by AI-powered search engines like ChatGPT and Google AI Mode.

HUMAN MOTOR PATTERNS S.R.L.

Innovative startup offering a patented medical device using machine learning and specialist clinicians for prevention, diagnosis, and rehabilitation of movement disorders.

OHMSPACE S.R.L.

Aerospace startup specialising in electric propulsion systems for spacecraft, developing high-efficiency thrusters for the next generation of space infrastructure.

PAGINA 75 S.R.L.

PAGINA 75 S.R.L. creates innovative digital content and media solutions.

POLIS POLITICS S.R.L.

Civic education platform empowering younger generations to become informed and engaged citizens in their communities.

PRINCIPLED INTELLIGENCE S.R.L.

PRINCIPLED INTELLIGENCE S.R.L. develops responsible and ethical AI solutions for enterprises.

RENT2CASH SRL

Cash in your future rents today.

Radical Storage

Radical Storage, founded in Rome in 2016, is a global luggage storage platform. Through a network of 15,000 partner locations in over 2,000 cities, it offers travelers security and flexibility in managing their luggage. It has raised over €10M in VC funding.

STRADA ARTIFICIAL INTELLIGENCE SRL

U-space service provider (USSP) offering an advanced drone traffic management platform in strategic partnership with Aloft, certified by ENAC.

SWITCH S.R.L.

SWITCH uses AI and simulation to revolutionise urban mobility and logistics, optimising traffic flow and last-mile delivery for smarter cities.

TRACTION GROUP S.R.L.

Digital marketing agency designing and building automated, multichannel customer experiences with a focus on marketing automation and CRM integration.

Translated

Translated, founded in 1999, offers professional translation and localization services powered by artificial intelligence. It serves over 380,000 clients worldwide and is a partner of major tech companies such as Google and Amazon.

WETACOO S.R.L.

Storage, moving, logistics for individuals and businesses. All managed with just a few clicks. Reliable transport throughout Italy. Offices in Rome, Milan, Turin.

VCs, accelerators and key players

Key sectors in Roma

spacetechgovtechcybersecurityhealthtech

What we can learn

  • Institutional poles can become advantages if demand cycles are unlocked
  • Research without patient capital does not generate enough scaleups
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